Posts Tagged ‘suppression’

Project 5: Response and Resistance Mechanisms

Exploiting Mechanisms of Response and Resistance to Next Generation Androgen Pathway Antagonists Co-Leaders: Elahe Mostaghel, M.D., Ph.D., Stephen Plymate, M.D. The efficacy of agents targeting the androgen receptor (AR) axis in men with castration-resistant prostate cancer (CRPC) may differ markedly based on tumor-specific differences in the induction of AR pathway components. A ...

The role of alternative splicing in the regulation of the KLF6 tumor suppressor gene

Goutham Narla, M.D., Ph.D., Assistant Professor, Departments of Genetics & Medicine; Director, Physician Scientist Training, Residency Program, Mount Sinai School of Medicine