Posts Tagged ‘androgen deprivation therapy’

Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

Harris WP, Mostaghel EA, Nelson PS, Montgomery B; Medscape. Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion. Nat Clin Pract Urol. 2009 Feb;6(2):76-85. PubMed PMID: 19198621. Androgen deprivation therapy remains a critical component of treatment for men with advanced prostate cancer, and data support ...

Association of megalin genetic polymorphisms with prostate cancer risk and prognosis

Holt SK, Karyadi DM, Kwon EM, Stanford JL, Nelson PS, Ostrander EA. Association of megalin genetic polymorphisms with prostate cancer risk and prognosis. Clin Cancer Res. 2008 Jun 15;14(12):3823-31. PubMed PMID: 18559602. PURPOSE: Megalin, an endocytic receptor expressed by prostate epithelial cells, can internalize biologically active androgens bound to ...