Cores

Specialized Programs of Research Excellence (SPORE) … promoting interdisciplinary research and moving basic research findings from the laboratory to clinical settings…

 

The PNW Prostate Cancer SPORE consists of four institutions that have large, multi-disciplinary teams of investigators and laboratories dedicated to prostate cancer research and a history of working closely together within this larger milieu. The respective teams of clinicians and researchers at these institutions bring considerable scientific depth and breadth required for confronting the most challenging problems blocking progress in our ultimate goal of reducing the morbidity and mortality associated with prostate cancer. This SPORE provides the blueprint for building a large coordinated translational prostate cancer effort spanning the Pacific Northwest.

The consortium aims to focus on finding molecular and other factors associated with the risk of prostate cancer recurrence and progression as well as its response – and resistance – to treatment. To this end, it is structured around five research projects, some ongoing and some new. Supporting these research projects are four shared resource cores:

 

Core A: Leadership & Administration

Co-directors: Peter Nelson, M.D., Janet Stanford, Ph.D., Paul Lange, M.D.

The ongoing successful functioning of the PNW prostate cancer SPORE is highly dependent upon the effective and efficient operations provided by the Administrative Core (Core A). This shared resource core is the hub for SPORE-related management, education, and communication within and across the four SPORE institutions…

 

Core B: Tissue & Specimen

Co-directors: Robert Vessella, Ph.D., Lawrence True, M.D.

The Specimen Core provides part of the infrastructure support for Projects 1 – 5 as well as for future pilot and developmental projects. It has been designed to meet the needs of these projects plus serve as a…

 

Core C: Biostatistics

Director: Ruth Etzioni, Ph.D.

The Biostatistics Core (Core C) provides essential biostatistical support to investigators of the PNW Prostate Cancer SPORE. This Core links study design, data collection, measurement, and analysis to the critical hypotheses and questions of the SPORE…

 

Core D: Clinical

Co-directors: John Gore, M.D., Evan Yu, M.D.

The Clinical Core of the PNW Prostate Cancer SPORE supports multiple areas relevant to clinical research, including independent clinical research trials spawning from the major projects, biospecimen acquisition, a repository for clinical data, and patient advocacy activities…